SEGMENTUM: A TOOL FOR COPY NUMBER ANALYSIS OF CANCER GENOMES

Segmentum: a tool for copy number analysis of cancer genomes

Abstract Background Somatic alterations, including loss of heterozygosity, can affect the expression of oncogenes and tumor suppressor genes.Whole genome sequencing enables detailed characterization of such aberrations.However, due to the limitations of current high throughput sequencing technologies, this task remains challenging.Hence, accurate a

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